Bad Bits of Hand Drawn Animation

Hand drawn animation is terrible. It takes so long to make movement look convincing and involves hours of tedious repetitive drawing. 3D animation creates smooth, natural movement more quickly and develops sprawling, beautiful scenery with detail and DEPTH that hand drawn animation can't accomplish.

Piper -Alan Barillaro

It's easier to experiment with trial and error when working in 3D than with 2D, where you must draw many rough frames and line test them before you know if it'll look good.

2D animation severely limits the degree to which you can move the camera, so you can't shoot a scene where the camera moves through a window and into a room. This makes it harder to tell a compelling story with exciting shots to convey a mood.

It's also harder to animate very subtle movements like breathing or natural movement when a character is in standby. This detracts from the illusion of life.